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 | | |  | | | | Antibody-drug conjugates (ADCs) are promisingly emerging anticancer therapeutics. The cytotoxic effects of chemotherapeutic drugs, combined with the antibodies targeting tumor-associated antigens (TAAs), make ADCs a fast-growing drug therapy for solid tumors. In addition to the well-established ADC target antigens, such as EGFR, FGFR, c-MET, and HER2, emerging targets like EpCAM, TROP-2, CD25, and others (Table 1) are under development and showing promising results in the treatment of solid tumors. | | Sino Biological is at the forefront of supporting the field of ADC therapy for the treatment of solid tumors by providing quality products for ADC target antigens. | | Table 1: ADC target antigens at the preclinical and clinical stages | | Various categories of ADCs in clinical and preclinical stages | ADC target antigens | | Well-established ADC TAAs | HER2, EGFR, EGFRvIII, c-MET, FGFR2, FGFR3 | | ADC TAAs overexpressed on cancer cells | EpCAM, BCMA, TROP-2, AXL, HER3, CD166, CEACAM5, GPNMB, Mesothelin, CD70 | | Target antigens in TME | CD25/IL2R, B7-H3, ANTXR1 | | Target antigens in CSCs | PTK7, ROR1, 5T4 | | | |  | | | | Sino Biological offers high-quality products for ADC therapy that have been validated for activity, and are trusted by users as indicated by citations in top-tier journals. | Learn More ! | | | Featured Recombinant Proteins for ADC Therapy | | | 
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Cited by Researchers | | | | Human EGFR Protein(Cat#: 10001-H27H-B) | Human CD25/IL2R alpha Protein(Cat#: 10165-H08H) |  |  | | Immobilized Human EGF (Cat#: 10605-H01H) can bind Human EGFR | Ability to inhibit IL2-induced proliferation of M07e cells | | | | Human c-MET Protein(Cat#: 10692-H08H) | Human BCMA Protein(Cat#: 10620-H08H) |  |  | | Immobilized Cynomolgus HGF (Cat#: 90286-CNAH) can bind Human c-MET | Immobilized Human BAFF (Cat#: 10056-H01H) can bind Human BCMA | | | | | Click Here for More ADC Target Antigens! | | Other Related Proteins | | | | | | |
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