Thursday, March 14, 2024

Today in Science: Why children’s meds are not fully tested

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Today In Science

March 13, 2024: Untested children's meds, cooling in reforested areas and plenty of TikToks.
Robin Lloyd, Contributing Editor
TOP STORIES

Reforestation Is Cool

Reforestation could be partly responsible for comparatively cooler weather in several eastern U.S. states, despite climate change, new research suggests. A great deal of the region's land initially was cleared to grow crops in the 19th century. But in the 20th century, croplands were abandoned as people moved into growing cities. This trend gave trees a chance to regrow. The study found that by the end of the 20th century, air temperatures on the hottest days were up to 1.8 degrees Fahrenheit (one degree Celsius) cooler in reforested areas than in nearby areas without forest, reports science journalist Jude Coleman. The cooling effect was most pronounced at midday in the summer, lowering surface temperatures by up to nine degrees F (five degrees C).

How they did it: Using satellite, historical temperature and weather station data, ecologist Kim Novick and her colleagues compared how surface and air temperatures varied between forested and nonforested areas. Then the team examined how temperatures fluctuated as forests regenerated between 1900 and 2010. 

Why it matters: Benefits would come with encouraging trees to regrow in historically forested areas or in moist temperate and tropical locations, experts say. Planting forests where none grew before could potentially harm the environment.
Top Story Image
A 1932 historical photograph of a 15-person planting crew in Tucker County, W.V. Credit: Library of Congress, Prints & Photographs Division, HABS WVA,47-PARS.V,1--33

Meds Untested in Kids

Most pharmaceutical drugs are developed and approved for use only in adults, reports journalist Frieda Klotz. As a result, children are usually prescribed medication "off-label," meaning the drug is being used differently from what's outlined on the package insert. The American Academy of Pediatrics has stressed that off-label prescribing does not necessarily entail great risk. However, the lack of proper testing puts children at a relatively higher risk of side effects. It also can leave doctors uncertain about the safety and effectiveness of medications in children. 

How this happened: For decades after the U.S. Food and Drug Administration reformed its drug approval process in the 1960s, regulators and medical ethicists argued that children should be excluded from pharmaceutical studies because they are a vulnerable population, at risk of exploitation by researchers. Nowadays, scientists agree that research is appropriately safe for children, who have much to gain from participating in such studies. 

What the experts say: "We now realize that we want to protect children with research," said pediatrician Mark Turner, who is involved in a European effort to support pediatric clinical trials. "We don't want to protect children from research." 
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A new technique helps scientists better understand how the world looks through the eyes of animals, as Scientific American editor Carin Leong explains in this TikTok
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The U.S. House of Representatives today passed a bill that could ban the app TikTok from all U.S. devices unless the app's China-based parent company ByteDance sells the widely used platform. The legislation now moves to the Senate, where its fate is uncertain. Some officials say the app currently can be used by the government of China for surveillance or propaganda. While you still can, enjoy two more highlights of Scientific American's TikTok collection
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—Robin Lloyd, Contributing Editor
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